Although oral isotretinoin or Accutane was approved by the Food And Drug Administration (FDA) in 1982, there were reports of potential side effects of the drug, linking it to depression and suicidal thoughts (1). The company discontinued manufacturing Accutane. However, it still distributes the generic versions of isotretinoin in the market. Isotretinoin is used to treat severe acne that does not respond to other forms of treatment. Since it is a derivative of vitamin A, doctors advise avoiding taking vitamin A supplements while on isotretinoin. Isotretinoin also has some serious side effects, including hair thinning and hair loss. Keep reading to find out how it is linked to hair loss.
Why Accutane May Cause Hair Loss
The exact mechanism of how isotretinoin causes hair loss is still unknown. However, a study found that it may cause alopecia areata (hair loss in patches) (2). More research is needed to arrive at a conclusion. In most cases, such hair loss is temporary, and people recover once the drug is discontinued. However, in some instances, hair loss can be permanent. Let’s find out what scientific research says about this.
What The Research Says
Research indicates that the drug may suppress the hormones present in the pituitary glands (2). This hormone suppression may help clear acne. However, it may also affect the hair growth rate. Another study suggested that isotretinoin taken in low dosage (0.5 mg/kg per day) may not affect the hair (3). However, using high doses of isotretinoin or retinoids may cause hair loss (4). Usually, doctors tailor the dosage of the drug, depending on the severity of acne. Unregulated use of isotretinoin may trigger hair loss. Wondering if the hair loss is permanent or not? Find out in the next section.
Does Accutane Cause Permanent Hair Loss?
No. Accutane will not cause permanent hair loss if you follow the dosage prescribed. You may experience hair fall, but it will subside once you stop taking isotretinoin. Doctors usually administer a low dosage, monitor the individual’s reaction to the drug, and then create a treatment plan. If you are experiencing hair loss while using isotretinoin, you may talk to your doctor for preventive measures or follow these tips.
Tips To Prevent Hair Loss While Using Accutane
Follow A Healthy Diet: Follow a healthy diet plan that includes vegetables, fruits, dairy, and meat. This will help prevent vitamin and mineral deficiencies and hair loss.
Avoid Vitamin A Supplements: An excess of vitamin A may cause hair loss and other complications. Hence, avoid taking vitamin A supplements while on isotretinoin treatment.
Stay Stress-free: Stress is a major reason for hair loss (7). That is why it is crucial to avoid stressing out. You may try meditation, take up a hobby, exercise, socialize, travel to different places, or do whatever keeps you happy.
The Takeaway
How common is hair loss on Accutane? Hair loss caused by isotretinoin isn’t that common. To minimize the likelihood of hair loss while taking an Accutane prescription, we must, however, take all reasonable precautions. This should be done by following doctors’ instructions and managing other factors. Can I take biotin while on Accutane? There were no interactions observed between Accutane and biotin. However, discuss with your doctor before you take them together.
